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Speaking from the heart: a mathematical point of view

de Oliveira, Diana Marta Cruz (2019) Speaking from the heart: a mathematical point of view. In: University of Birmingham Graduate School Research Poster Conference 2019, 19th June 2019, University of Birmingham 2019. (Unpublished)

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The mechanics associated with a living entity dictates its ability to survive or perish. Similarly, heart valve function relies on its mechanical properties and structural integrity. A compromise in these leads to diseased valve states. There are still many unknowns on the influence of dimensional changes in valve mechanics: to tackle this, we created a mathematical model describing the shape of a heart valve based upon clinical data. We then established a computational characterization associated with different valve configurations.
Our model predicted different cases of function, associated with valve geometrical changes. Diseased configurations, yielded greater valve tissue stress in comparison with healthy ones, exhibiting greater damaging. Our model provides with adjustable geometric detail, useful to study customized cases by employing diverse patient data and generating a range of geometries for computational assessment. Such framework can aid in patient risk stratification by indicating which configurations are associated with unfavorable performance.

Type of Work:Conference or Workshop Item (Poster)
School/Faculty:Colleges (2008 onwards) > College of Engineering & Physical Sciences
Department:Department of Mechanical Engineering
Additional Information:

Engagement Award Winner. Supervisors: Daniel Espino, Duncan Shepherd (University of Birmingham) & Keith Buchan (Aberdeen Royal Infirmary)

Date:19 June 2019
Series/Collection Name:Prizewinners from the Graduate School Research Poster Conference 2019
Subjects:Q Science > Q Science (General)
R Medicine > R Medicine (General)
T Technology > T Technology (General)
Related URLs:
Copyright Status:This poster is copyright of the author and/or third parties. The intellectual property rights in respect of this work are as defined by The Copyright Designs and Patents Act 1988 or as modified by any successor legislation. Any use made of information contained in this poster must be in accordance with that legislation and must be properly acknowledged.
Copyright Holders:The Author
ID Code:3233

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